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Showing posts with label Cholesterol. Show all posts
Showing posts with label Cholesterol. Show all posts

Sunday, May 26, 2013

Science Confirms Turmeric As Effective As 14 Drugs

Turmeric or Curcumin
Science Confirms Turmeric As Effective As 14 Drugs
 
Posted on:Monday, May 13th 2013 at 2:00 pm
Written By:Sayer Ji, Founder
Re-blogged from "WakingTimes"via "Ervas e Curas - O Glossário Herbal "

Science Finds Ancient Spice Turmeric As Effective As 14 Drugs
 
Science Finds Ancient Spice Turmeric As Effective As 14 Drugs

Turmeric is one the most thoroughly researched plants in existence today.  Its medicinal properties and components (primarily curcumin) have been the subject of over 5600 peer-reviewed and published biomedical studies.  In fact, our five-year long research project on this sacred plant has revealed over 600 potential preventive and therapeutic applications, as well as 175 distinct beneficial physiological effects. This entire database of 1,585 ncbi-hyperlinked turmeric abstracts can be downloaded as a PDF at our Downloadable Turmeric Document page, and acquired either as a retail item or with 200 GMI-tokens, for those of you who are already are members and receive them automatically each month.
Given the sheer density of research performed on this remarkable spice, it is no wonder that a growing number of studies have concluded that it compares favorably to a variety of conventional medications, including:

    Lipitor/Atorvastatin(cholesterol medication): A 2008 study published in the journal Drugs in R & D found that a standardized preparation of curcuminoids from Turmeric compared favorably to the drug atorvastatin (trade name Lipitor) on endothelial dysfunction, the underlying pathology of the blood vessels that drives atherosclerosis, in association with reductions in inflammation and oxidative stress in type 2 diabetic patients. [i]  [For addition curcumin and 'high cholesterol' research – 8 abstracts]
    Corticosteroids (steroid medications): A 1999 study published in the journal Phytotherapy Research found that the primary polyphenol in turmeric, the saffron colored pigment known as curcumin, compared favorably to steroids in the management of chronic anterior uveitis, an inflammatory eye disease.[ii]  A 2008 study published in Critical Care Medicine found that curcumin compared favorably to the corticosteroid drug dexamethasone in the animal model as an alternative therapy for protecting lung transplantation-associated injury by down-regulating inflammatory genes.[iii] An earlier 2003 study published in Cancer Letters found the same drug also compared favorably to dexamethasone in a lung ischaemia-repurfusion injury model.[iv]  [for additional curcumin and inflammation research – 52 abstracts]
    Prozac/Fluoxetine & Imipramine  (antidepressants): A 2011 study published in the journal Acta Poloniae Pharmaceutica found that curcumin compared favorably to both drugs in reducing depressive behavior in an animal model.[v] [for additional curcumin and depression research – 5 abstracts]
    Aspirin (blood thinner): A 1986 in vitro and ex vivo study published in the journal Arzneimittelforschung found that curcumin has anti-platelet and prostacyclin modulating effects compared to aspirin, indicating it may have value in patients prone to vascular thrombosis and requiring anti-arthritis therapy.[vi]  [for additional curcumin and anti-platelet research]
    Anti-inflammatory Drugs: A 2004 study published in the journal Oncogene found that curcumin (as well as resveratrol) were effective alternatives to the drugs aspirin, ibuprofen, sulindac, phenylbutazone, naproxen, indomethacin, diclofenac, dexamethasone, celecoxib, and tamoxifen in exerting anti-inflammatory and anti-proliferative activity against tumor cells.[vii] [for additional curcumin and anti-proliferative research – 15 abstracts]
    Oxaliplatin (chemotherapy drug): A 2007 study published in the International Journal of Cancer found that curcumin compares favorably with oxaliplatin as an antiproliferative agenet in colorectal cell lines.[viii] [for additional curcumin and colorectal cancer research – 52 abstracts]
    Metformin (diabetes drug): A 2009 study published in the journal Biochemitry and Biophysical Research Community explored how curcumin might be valuable in treating diabetes, finding that it activates AMPK (which increases glucose uptake) and suppresses gluconeogenic gene expression  (which suppresses glucose production in the liver) in hepatoma cells. Interestingly, they found curcumin to be 500 times to 100,000 times (in the form known as tetrahydrocurcuminoids(THC)) more potent than metformin in activating AMPK and its downstream target acetyl-CoA carboxylase (ACC). [ix]

Another way in which turmeric and its components reveal their remarkable therapeutic properties is in research on drug resistant- and multi-drug resistant cancers.  We have two sections on our site dedicated to researching natural and integrative therapies on these topics, and while there are dozens of substances with demonstrable efficacy against these chemotherapy- and radiation-resistant cancers, curcumin tops both lists:

    Cancers: Drug Resistant
    Cancers: Multi-Drug Resistant

We have found no less than 54 studies indicating that curcumin can induce cell death or sensitize drug-resistant cancer cell lines to conventional treatment.[x]
We have identified 27 studies on curcumin's ability to either induce cell death or sensitize multi-drug resistant cancer cell lines to conventional treatment.[xi]
Considering how strong a track record turmeric (curcumin) has, having been used as both food and medicine in a wide range of cultures, for thousands of years, a strong argument can be made for using curcumin as a drug alternative or adjuvant in cancer treatment.
Or, better yet, use certified organic (non-irradiated) turmeric in lower culinary doses on a daily basis so that heroic doses won't be necessary later in life after a serious disease sets in.  Nourishing yourself, rather than self-medicating with 'nutraceuticals,' should be the goal of a healthy diet.  [learn more at Sayer Ji's new collaborative project EATomology]
Resources

    [i] P Usharani, A A Mateen, M U R Naidu, Y S N Raju, Naval Chandra. Effect of NCB-02, atorvastatin and placebo on endothelial function, oxidative stress and inflammatory markers in patients with type 2 diabetes mellitus: a randomized, parallel-group, placebo-controlled, 8-week study. Drugs R D. 2008;9(4):243-50. PMID: 18588355

    [ii] B Lal, A K Kapoor, O P Asthana, P K Agrawal, R Prasad, P Kumar, R C Srimal. Efficacy of curcumin in the management of chronic anterior uveitis. Phytother Res. 1999 Jun;13(4):318-22. PMID: 10404539

    [iii] Jiayuan Sun, Weigang Guo, Yong Ben, Jinjun Jiang, Changjun Tan, Zude Xu, Xiangdong Wang, Chunxue Bai. Preventive effects of curcumin and dexamethasone on lung transplantation-associated lung injury in rats. Crit Care Med. 2008 Apr;36(4):1205-13. PMID: 18379247

    [iv] J Sun, D Yang, S Li, Z Xu, X Wang, C Bai. Effects of curcumin or dexamethasone on lung ischaemia-reperfusion injury in rats. Cancer Lett. 2003 Mar 31;192(2):145-9. PMID: 18799504

    [v] Jayesh Sanmukhani, Ashish Anovadiya, Chandrabhanu B Tripathi. Evaluation of antidepressant like activity of curcumin and its combination with fluoxetine and imipramine: an acute and chronic study. Acta Pol Pharm. 2011 Sep-Oct;68(5):769-75. PMID: 21928724

    [vi] R Srivastava, V Puri, R C Srimal, B N Dhawan. Effect of curcumin on platelet aggregation and vascular prostacyclin synthesis. Arzneimittelforschung. 1986 Apr;36(4):715-7. PMID: 3521617

    [vii] Yasunari Takada, Anjana Bhardwaj, Pravin Potdar, Bharat B Aggarwal. Nonsteroidal anti-inflammatory agents differ in their ability to suppress NF-kappaB activation, inhibition of expression of cyclooxygenase-2 and cyclin D1, and abrogation of tumor cell proliferation. Oncogene. 2004 Dec 9;23(57):9247-58. PMID: 15489888

    [viii] Lynne M Howells, Anita Mitra, Margaret M Manson. Comparison of oxaliplatin- and curcumin-mediated antiproliferative effects in colorectal cell lines. Int J Cancer. 2007 Jul 1;121(1):175-83. PMID: 17330230

    [ix] Teayoun Kim, Jessica Davis, Albert J Zhang, Xiaoming He, Suresh T Mathews. Curcumin activates AMPK and suppresses gluconeogenic gene expression in hepatoma cells. Biochem Biophys Res Commun. 2009 Oct 16;388(2):377-82. Epub 2009 Aug 8. PMID: 19665995

    [x] GreenMedInfo.com, Curcumin Kills Drug Resistant Cancers, 54 Abstracts

    [xi] GreenMedInfo.com, Curcumin Kills Multi-Drug Resistant Cancers: 27 Abstracts.


Re-blogged from "WakingTimes" via "Ervas e Curas - O Glossário Herbal "
German Translation by (Contra)Mary
Publicada por curadora64
  
 
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Wednesday, May 22, 2013

…and read here what Garlic can do for your Health !


Posted on May 22, 2013 by
Re-blogged from Waking Times

How Garlic Can Save Your Life

May 21, 2013 | By | Reply
Flickr - Garlic - SantaRosa OLD SKOOLSayer Ji, Green Med Info
Waking Times
Research on garlic indicates that it may provide an ideal low-cost and safe alternative to drugs and vaccines in reducing the three most common causes of death in the world.
In a world mesmerized by the false promises of pharmaceutical industry marketing copy, as well as inundated with aggressively marketed dietary supplements, many of which are manufactured by the same companies making a killing off patented chemicals (Bayer owns One A Day, Pfizer owns Centrum), it is reassuring to know that the kitchen pantry will never fail us…
Inexpensive, time-tested, safe and delicious, many spices are attaining recognition for being, quite literally, 'life saving,' which is likely one reason why, in ancient times, many were worth their weight in gold.
This time around, the health benefits of ancient 'folk remedies' like garlic are being confirmed by straight-laced men and women in lab coats. Which, when it comes to the conventional medical establishment, blighted as it is by the epistemological disease known as myopia, is considered the only valid way to ascertain the truth. Never mind the countless millions of people who, since the beginning of time, have used a different standard of proof: if it works and it is safe, then its true.
We all know that garlic is not shy to make its presence known. The smallest culinary dose is enough to suffuse the entire body with its aroma. Garlic also permeates the research literature: the biomedical database known as MEDLINE, provided by the National Library of Medicine, contains 4245 study abstracts on garlic, a number of which we have indexed and organized for your use on our site: Health Benefits of Garlic.
A cursory perusal of the literature there indicates that garlic has a significant role to play in preventing or treating well over 150 health conditions, ranging from cancer to diabetes, infection to plaque buildup in the arteries, DNA damage to mercury poisoning.
In fact, a strong argument can be made (pun intended) that expanding the availability of garlic around the world as both a food and a medicine could prevent millions of deaths annually. According to World Health Organization statistics, the populations of poorer countries die manly from causes directly connected to communicable infectious diseases, which incidentally are not caused by a lack of vaccines, rather, primarily through under-nutrition and malnourishment, lack of sanitation and hygiene, as well as the adverse physiological consequences of the depression and stress associated with poverty.  The greater use and availability of garlic might provide a perfect alternative to global vaccine initiatives, the use of which are driven less by compelling scientific research, and more by political and economic forces. Garlic is easier to acquire and distribute, and can often be grown by the affected persons or communities affected, making it essentially free.

Garlic Versus #1 Cause of Death for the Poorest Countries

As far as the research goes, garlic has immensely powerful anti-infective properties, experimentally confirmed to kill the following:
  1. Methicillin Resistant Staphylococcus Aureus (MRSA)[1], [2]
  1. Thrush (Fungal overgrowth in oral cavity)[3]
  2. Pseudomonas Aerigonosima, including drug-resistant strains.[4][5][6]
  3. Cytomegalavirus Infections[7] [8] [9] [10]
  4. Mycotoxin-associated aflatoxicosis[11] [12]
  5. Helicobacter Pylori infection[13]
  6. Candida (Yeast) infection[14] [15] [16]
  7. Klebseilla infection[17] [18]
  8. HIV-1 infection[19] [20]
  9. Vibrio infection [21] [22]
  10. Mycobacterium Tuberculosis, multi-drug resistant[23]
  11. Clostridium infections[24]
  12. Viral Infections:  Herpes Simplex 1 and 2, Parainfluenza virus type 3, vaccinia virus, vesicular stomatitis virus and human rhinovirus type 2.
  13. Group B Streptococcus Infection[25] [26]


This is an impressive smattering of research, but it is likely only the tip of the iceberg when it comes to garlic's ability to fight infection.  Remember, a lack of scientific proof does imply a lack of efficacy. Given that conventional antibiotics are not only failing, but driving bacteria and viruses into greater lethality, we can't wait around for the multi-billion dollar clinical trial-based drug approval process to turn its attention to a non-patentable natural substance.  Such a profit-oriented approach would be highly unethical.

Garlic Versus the Developed World's #1 and #2 Killers

The research on Greenmedinfo.com shows garlic has value in 167 health conditions or disease symptoms, but the greatest density of research indicates garlic's role in preventing and/or treatingCardiovascular Disease and Cancers, the two primary causes of death within high-income countries.[27]
This is an interesting finding. The drug industry has been fantasizing about a so-called 'polypill' for quite some time, an idea involving mixing various patented medicines together for a condition like heart disease (e.g. blood pressure, cholesterol, blood thinner), but to no avail. Patented chemicals have far too many side effects, so when you mix them together, you only compound their multitudinous chemical toxicities. Natural substances, on the other hand, and especially those which play a role in culinary traditions as "spices," appear to have the opposite karma. Namely, they have far more 'side benefits' than 'side effects.'
Garlic's cardioprotective effects include:
  1. Retards progression of arterial plaque[28] [29] [30]
  2. Beneficially decreases white adipose tissue, increases white adipose tissue around heart muscle.[31]
  3. Protects against clotting[32] [33]
  4. Positively modulates blood lipids[34],[35],[36]
  5. Vasodilator[37]
  6. Reduces blood pressure[38]
  7. Antioxidant[39]
  8. Endothelial Dysfunction[40] [41]
  9. Vascular Inflammation[42]
Here is a quick review of the cancers that garlic has been found to kill:

  1. Acute Lymphoblastic Leukemia[43]
  2. Acute Myeloid Leukemia[44]
  3. Basal Cell Carcinoma[45]
  4. Breast Cancer[46],[47]
  5. Cervical Cancer[48]
  6. Colon Cancer[49]
  7. Endometrial Cancer[50] [51]
  8. Gastric Cancer[52] [53]
  9. Leukemia: Chronic Lymphocytic Leukemia (CLL)[54]
  10. Liver Cancer[55] [56] [57]  [58]
  11. Lymphoma[59] [60]
  12. Melanoma[61
  13. Osteosarcoma[62]
  14. Pancreatic Cancer[63]
Garlic, like so many other complex foods, contains a wide range of phytocompounds that articulate at least 150 distinct physiological responses in the mammalian body (see our 157 pharmacological actions list on the Garlic Research page).
How can this be so?
One explanation is that all foods contain not only physical building blocks, e.g. carbs, proteins, lipids, and are not only a source of energy (caloric content), but contain gene and epigene regulatory information. There are 'packets' of energy and information contained within the conformational state of the biomolecules found within these plant tissues. Our co-evolution with the plant kingdom for the past half a billion years has resulted in the very genetic/molecular fabric of our body depending on certain key compounds from plants in our diet, delivered in natural form, not irradiated, overly-cooked, petrochemically-farmed. Garlic's ability to fit like a key, into many different types of locks (an impossible feat for monochemical 'magic bullets'), reflects an likely infinitely complex intelligence in the relationship between plant and animal species. Which speaks to how important foods are not simply as 'medicine,' but that from which our bodily health grows organically, and without which disease is a natural consequence.
About the Author
Sayer Ji is an author, researcher, lecturer, and advisory board member of the National Health Federation.
He founded Greenmedinfo.com in 2008 in order to provide the world an open access, evidence-based resource supporting natural and integrative modalities. It is internationally recognized as the largest and most widely referenced health resource of its kind.

Resources
Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of WakingTimes or its staff.
This article is offered under Creative Commons license. It's okay to republish it anywhere as long as attribution bio is included and all links remain intact.
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Tuesday, May 21, 2013

Dandelions - Bright little Suns - and also healthful Nutriment !

Re-blogged from "Laura Bruno'Blog"
Here is another delightful recipy of Laura Bruno, the "Queen of Dandelions" (as I call her by myself .... If you scroll down you will find her post about Dandelions re-blogged hereunder on my blog.

And believe me - I followed her sequence and prepared - for rhe first time in my life - some gren smoothie made from Dandelion Blossoms and Leaves ... and I like it much ... not only me but my body all the more !!!
 
And here is another one of her delicious recepies which I want to share with all of you hereunder:
With Compassionate and Unconditional Love to All of You
(Contra)Mary

New post on Laura Bruno's Blog


Goji Dandelion Red Lentil Curry

by laurabruno
I haven't posted any recipes in awhile, but this one was too tasty not to share!

As regular blog readers know, I've got a yard full of dandelions, and aside from harvesting the flowers for dandelion wine and dandelion jelly, I also gather dandelion leaves. Bags and bags of dandelion leaves! Sometimes I put them in green smoothies with frozen pineapple, banana and filtered water. Sometimes I steam them and just top with a hint of sea salt and freshly ground pepper. And sometimes I've been known to eat them wrapped around a slice of raw manchego. Tonight, I decided to make a dandelion soup.

Dandelions

Goji soup ingredients

I don't measure when I prepare food, but here's a guestimate:

Goji Dandelion Red Lentil Curry

Ingredients:

1.5 cups dried red lentils
filtered water to cover the lentils
1 strip of kombu seaweed
1 clove of garlic, pressed

half bag of gathered dandelion greens
half bunch of cilantro (not pictured)

three handfuls of dried goji berries
1 16 oz. can of coconut milk
Thai Kitchen green curry paste to taste (I used two generous scoops)

Method:

Cover the lentils with filtered water and begin to boil. Add in the kombu (for better digestion) and a clove of pressed garlic.

As the lentils and water begin to boil, put the dandelion greens and cilantro into a blender. Add enough filtered water (not the boiling water, but more water) to blend the greens into about a quart of nice, bright green liquid.

Add the blended water and greens to the pot of lentils and continue to boil. Watch to make sure the lentils don't foam over. Turn down to low once you've established a rolling boil, at which point, you can add the three handfuls of goji berries and let it all simmer.

When the lentils are soft --about twenty to thirty minutes -- add the coconut milk and green curry paste. Simmer for ten more minutes to meld the flavors. Serve and add a hint of sea salt to taste.

Goji soup

Goji berries hail from the nightshade family, just like tomatoes. Asians often add them to soups in order to impart a rich sweetness. In this soup, they perfectly balance the bitterness of the dandelions and go well with the subtle cilantro flavors. The spicy-sourness of the green curry rounds out the flavors, with the kombu adding that hint of fish flavor usually found in non-vegan curry dishes.

I got the idea for this soup while craving red lentils, noticing that I really needed to use up the rest of our cilantro, and researching where to plant my two new goji berry bushes:

Goji plants

Apparently, the bushes love full sun and can grow to sizes of eight to twelve feet in height and diameter. That's a lot of goji berries! It also requires careful planning, since they like to spread once happily planted in their spot. I haven't decided whether to plant them next to each other (with space in between) for a full goji hedge -- a "fedge" (food hedge) in permaculture speak -- or if I want to plant them in different areas to increase the odds of finding appropriate growing conditions. In the meantime, I will definitely add goji berries to soups again! Also known as wolfberries, these little gems pack a nutritional wallop: from beta carotene to anti-oxidants to fountain of youth chemicals and blood thinning capability.

Although I still consume the vast majority of my food raw, some things benefit from cooking. The boiling process mellows the sugars of the dried, sticky goji fruits, and it allows the dandelion greens to form a short-term herbal infusion, making some of the nutrients more bio-available than in their raw state. Besides helping with allergies and providing high vitamin A and calcium, dandelion greens offer so many benefits that I'm just sending you to the following link: click here to read a long list of dandelion health benefits. The results of eating kombu include: vitality and youthfulness, detoxification, adding essential trace minerals, and easier digestion of legumes.

Speaking of legumes, the red lentils made the list of the top ten healthy foods, due to their high fiber, high antioxidants, magnesium and folate. Additionally, scientists recently found a compound in nuts and lentils that blocks the growth of cancerous tumors.

Cilantro chelates mercury and heavy metals, and garlic does everything from boost immunity to thinning blood to keeping away vampires --psychic and otherwise. ;) Coconut milk contains phosphorous for strong bones and manganese for good blood sugar levels, along with Omega 3, 6 and 9 fatty acids and various amino acids. A healthier option would involve cracking your own coconut to avoid the BPA in cans; however, I keep these cans on hand for very occasional, spontaneous meals. I'm a Lazy Raw Foodist even when I cook! The Thai Kitchen brand of curry pastes, including this green paste, are (as far as I can tell at this time) vegan. I keep both red and green flavors on hand, because they make fabulous soups and nori wraps on very short notice.

Most importantly for my purposes tonight, this superfood soup tasted savory, sweet, tangy and all around amazing! It had so many rich flavors that I can't believe I only used water and no vegetable broth. TGWHL: Thank God/dess We Have Leftovers! :)






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Your Garden will not green-grow
-if you do not water it properly-